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Indianapolis Colts, San Francisco 49ers

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 · 7m
49ers vs. Colts Prediction, Odds, Spread, Injuries, Trends for NFL Week 16
The Philip Rivers story continues in Week 16 when he gets the start for the Indianapolis Colts on Monday Night Football against the San Francisco 49ers.

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 · 8h · on MSN
49ers at Colts: Predictions, picks and odds for Monday Night Football
Colts Wire on MSN · 5h
Announcers set for Colts vs. 49ers Monday Night Football matchup

Ricky Pearsall, San Francisco 49ers

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Top News
Overview
 · 21h · on MSN
What 49ers' Ricky Pearsall's latest injury says about him
Pearsall's status will be up in the air when the 49ers face the Indianapolis Colts on Monday night. As a result, he's back to entering injury-prone territory.

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 · 1d
49ers' Ricky Pearsall faces new injury setback after standout performance in win vs. Titans
USA TODAY Touchdown Wire on MSN · 1d
49ers get tons of good injury news, Ricky Pearsall avoids disaster
Santa Rosa Press Democrat · 1d
49ers won’t determine Ricky Pearsall’s availability until later in the week
Things are looking good in terms of injuries for the 49ers coming out of a 37-24 win over the Tennessee Titans, but the status of wide receiver Ricky Pearsall Jr. won’t be known until later in the wee...

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 · 1d
49ers' Ricky Pearsall's status for MNF uncertain after dual injuries vs. Titans
 · 1d
49ers plan to bring speedy WR off IR after long injury absence

49ers move up again in newest power rankings

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Overview
Niners Wire on MSN · 17h
Brock Purdy passes 3-time All-Pro in 49ers' career passing leaders
San Francisco 49ers quarterback Brock Purdy has been a stud since taking over as the team's starter after Jimmy Garoppolo went down with an injury in 2022.

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 · 1d
Purdy's 3 TD passes lead 49ers to 37-24 win over Titans
 · 1d
49ers move up again in newest power rankings after win vs. Titans
Niners Wire · 9h
49ers vs. Titans highlights: SF extends win streak to 4 games
The San Francisco 49ers managed to keep the Tennessee Titans at arm's length Sunday and earned a 37-24 win for their fourth consecutive victory.

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 · 1d
Titans report card: How we graded Tennessee in Week 15 loss to 49ers
 · 1d
Best photos from 49ers vs. Titans in Week 15

As Rams, Seahawks vie for top seed, 49ers are lurking

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Overview
 · 7h
NFC West roundtable: As Rams, Seahawks vie for top seed, 49ers are lurking
The Rams could all but clinch the top seed Thursday, but a Seahawks win would put Seattle in control ... and open the door for the 49ers.

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Rams Wire · 23h
How a win or loss vs. Seahawks will impact Rams' odds to win NFC West
 · 1d
NFC West playoff scenarios: What Rams and Seahawks need next
 · 12h
Seattle Seahawks
The Seattle Seahawks entered the NFL as an expansion team in 1976.

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 · 22h
Breaking down the path for the 49ers to get the No. 1 seed
 · 1d
NFC West standings: Rams maintain lead with critical Week 16 game coming
27mon MSN

One Area That is Becoming a Weakness for the 49ers

It’s been nothing short of incredibly impressive for the San Francisco 49ers to be 10-4. With so many injuries to star and key players, they should’ve been sunk
25m

Trade buzz: What teams could be looking to trade for 49ers' Mac Jones?

After becoming a major impact on the San Francisco 49ers' success in 2025, QB Mac Jones could be traded to a quarterback-needy team.
SB Nation on MSN
1h

Why the 49ers should put in a waiver claim for Dolphins recently released pass rusher

Judon would have to get through a handful of potential playoff teams before reaching the 49ers in the waiver wire. That includes his former team, the Ravens, and other teams like the Bucs, Lions, and Packers that need pass-rush help.
Niners Wire on MSN
3h

Former NFL QB believes 49ers would be dangerous in the playoffs

The San Francisco 49ers currently hold a playoff spot, and at least one analyst thinks they could be dangerous if they make it.
2hon MSN

The 49ers are lurking, and that’s probably how they like it

Here’s one very realistic outcome, if the Seahawks beat the Rams on Thursday night. With a 4-1 record in the division and a split with the Rams, the 49ers would win any tiebreakers with the Rams or Seattle (which the 49ers beat in Week 1).
2hon MSN

These San Francisco 49ers should make the 2025 Pro Bowl

The Pro Bowl voting just ended for fans, and in a week or two, the teams will be announced. The San Francisco 49ers had a few players crack the top ten in fan voting, but that is only ⅓ of the vote. Which 49ers players may get the honour?
Niners Wire on MSN
1h

49ers can bolster Super Bowl chances with this signing

Through 15 weeks, the 49ers have recorded just 16 sacks, which is the fewest in the league. It's six sacks fewer than the New York Jets and Baltimore Ravens who have the next fewest. While trading for Keion White and signing Clelin Ferrell has helped, San Francisco could still use more to give them a better shot of making a postseason run in 2025.
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