A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell. The work, published Jan. 29 in Nature Communications, reveals a new signaling mechanism ...

Mode of action of the new microscopy method LLS-TDI-DNA-PAINT. On the top right, the RTX antibody was visualised on a Raij-B cell: it is easy to see how it links the CD20 molecules in the membrane.

In the search for new drugs for a range of diseases, he uses high-throughput and high-content screens to determine the mechanisms of action of novel compounds. Several of his primary antibodies ...

Until now, research has assumed that therapeutic antibodies of type I have a different mechanism of action than those of type II. However, the Würzburg studies disprove this. "The hedgehog shape ...

This article explores how broadly neutralizing antibodies are being researched, not only for their potential in the prevention of HIV, but also for other rapidly mutating viruses such as influenza and ...

Bispecific antibodies, which bind simultaneously to two different antigens, can attack tumors via novel mechanisms of action that cannot be evoked with combinations of conventional monoclonal ...

Until now, research has assumed that therapeutic antibodies of type I have a different mechanism of action than those of type II. However, the Würzburg studies disprove this. 'The hedgehog shape ...