Prostate tumors can rewire amino acid metabolism to override the normal brakes on cholesterol production, a process that may ...

A new study shows how prostate cancer cells use valine and isoleucine metabolism to sustain cholesterol synthesis under ...

This review illustrates amino acid metabolic reprogramming in breast cancer, highlighting its role in tumor progression and clinical applications, including diagnostic imaging, targeted therapies, ...

The review introduces the molecular subtypes of breast cancer and outlines how altered amino acid metabolism supports tumor growth. It explores key amino acid pathways—including glutamine, serine, ...

Researchers at Weill Cornell Medicine have identified a metabolic process that may help explain why some prostate cancers ...

Changes to the intermediate filament (IF) protein, vimentin, were found to promote tumor growth by increasing cancer stemness in an oestrogen independent manner. Targeting vimentin and/or the long ...

Brain metastases often occur as a result of advanced cancer, and despite medical innovations, are still associated with a poor prognosis. Now, an international expert committee led by the Medical ...

The immune system constantly checks the body’s cells for signs of trouble, but that surveillance depends on cells being able to send the right signals. A new study from The Rockefeller University ...

This week's topics include tranexamic acid for liver resection, edetate disodium (EDTA)-based chelation therapy, suicidality among spouses of people with cancer, and do amino acids protect kidneys ...