A team of chemists from the University of Vienna, led by Nuno Maulide, has achieved a significant breakthrough in the field of chemical synthesis, developing a novel method for manipulating ...

Disulfide bonds play a pivotal role in the folding and stability of many bacterial proteins, influencing not only their tertiary structure but also their biological activity. In bacteria, the ...

Prior to 2000, many drugs that formed a covalent bond with targets did so non-selectively, which often led to undesired side effects when compared to non-covalent drugs. This led to the belief that ...