Embryonic development is one of the most dynamic biological processes in nature. Cells and tissues organize and reorganize ...

Paxillin is a multi‐domain adaptor protein central to the formation, maturation and disassembly of focal adhesions, the dynamic complexes by which cells adhere to the extracellular matrix and ...

Focal adhesions are dynamic multi-protein assemblies that anchor the intracellular actin cytoskeleton to the extracellular matrix, thereby converting mechanical stimuli into biochemical signals.

Scientists find that close interactions between the mechanical properties of tissues and biochemical signalling between cells ...

This graphic illustrates paracrine adhesion signaling on small extracellular vesicles, which secretes a protein called galectin-3, which promotes endocytosis so the vesicle can be absorbed into the ...

Within the past decade, biologists have discovered that one strategy cells use to keep their contents organized is a ...

For the first time, scientists have succeeded in artificially mimicking the ion signaling of heart muscle cells. To succeed, ...

Cellular phase separation may play a previously underappreciated role in regulating kinase activity, offering therapeutic ...