Among the many marvels of life is the cell's ability to divide and thus enable organisms to grow and renew themselves. For this, the cell must duplicate its DNA—its genome—and segregate it equally ...

For sexual reproduction to yield healthy offspring, newly generated oocytes—immature egg cells—must receive the correct amount of DNA after cell division. This process of segregating chromosomes ...

Researchers created artificial kinetochore structures that reduce chromosome separation errors during meiosis in aging egg cells. By lowering microtubule pulling force, the approach helped maintain ...

As the cell proceeds through the stages of cell division (from left to right: interphase, prometaphase, metaphase, and anaphase), chromosomes become progressively more compact through a combination of ...

New findings shed light on how chromosomes manage the various pushing and pulling forces generated when cells divide. Specifically, researchers show that chromosomes resist being punctured by the ...

A remarkably small bacterium containing fewer than 500 genes serves as the basis for one of the most detailed digital life ...

A study explains how broken DNA during cell division can trigger chromoanasynthesis when two repair pathways combine, causing ...

By simulating the life cycle of a minimal bacterial cell—from DNA replication to protein translation to metabolism and cell division—scientists have opened a new frontier of computer vision into the ...

Accurate chromosome segregation and cell division are central to maintaining genomic integrity and ensuring proper development and tissue homeostasis. These processes rely on a complex network of ...

Loss of the Y chromosome in aging men is widespread and increasingly linked to serious diseases, challenging assumptions that ...

Researchers have discovered key mechanisms and structural details of a fundamental biological process -- how a cell nucleus and its chromosomal material reorganizes itself after cell division. The new ...

For a living cell to divide successfully, each daughter cell must inherit the correct genetic material. In eukaryotes, segregation of duplicated chromosomes is performed by the mitotic spindle, a ...