Deep inside a small, windowless room at the University of California, Berkeley, two microscopes are quietly capturing some of ...

How large, fully folded proteins can pass through cell membranes without destroying them has long been one of the open questions in cell biology. Using cryo-electron microscopy (cryo-EM), Leonid ...

Nearly 100 years ago, a seemingly simple discovery revolutionized the microscope. The introduction of phase contrast, which ...

Fluorescence microscopy has become an indispensable tool to investigate the dynamics of macromolecules directly in living cells on length scales ranging from the nanoscale via super-resolution ...

Fluorescence microscopy offers unparalleled access to the spatial organization and dynamics of biological events in living samples, yet capturing rare processes over extended durations remains ...

Identifying and delineating cell structures in microscopy images is crucial for understanding the complex processes of life. This task is called "segmentation" and it enables a range of applications, ...

Microscopy is an imaging technique that enables us to see a world that would otherwise be invisible to us. Once upon a time, visualizing cells, microbes and other entities not perceptible to the naked ...

Using an innovative combination of biochemical experiments and ultra-high-resolution microscopy, a research team at Kiel ...

Bioengineers bridge the gap between spectroscopy developers and biologists through a systematic guide explaining modern Raman ...

Laser-driven thermoviscous flows provide contact-free rotation, transport or stabilization of delicate samples such as ...

In blood cancers such as chronic lymphocytic leukemia, B cells of the immune system multiply uncontrollably. One form of therapy involves labeling the CD20 protein on the surface of the B cells with ...

Confocal microscopy is a specialized fluorescence imaging technique that scientists use to acquire images at greater resolution than conventional microscopy. 1 In addition to scanning the lateral x ...