FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...

Sterols, such as cholesterol in our bodies or ergosterol in yeast cells, are among the most abundant lipids in eukaryotic cells, yet are synthesized through notoriously long, complex metabolic ...

A deep dive into lipid genetics reveals how ancestry-specific molecular pathways could be driving higher diabetes and heart disease risk, bringing researchers closer to more precise, ...

Cholesterol plays a vital role in the body, providing structural support to cells and serving as a building block for hormone synthesis. However, when cholesterol accumulates or is improperly ...

AD is associated with significant changes in genes related to neuroinflammation, and lipids are crucial in this metabolic dysregulation. Abnormal phospholipid accumulation in the brain not only ...

Pancreatitis is a complex inflammatory disease driven by both genetic and environmental factors. It poses substantial ...

An international collaboration of genetic researchers has identified more than 90 genetic regions associated with the risk of ...

Phase 1 clinical data poster selected as a Best of EASL 2026 presentationCombination of denifanstat and resmetirom was generally well-tolerated ...

A single enzyme in the brain quietly dismantles the receptors neurons need to clear amyloid, the toxic protein that ...