In summary, we have reported the first method for catalytic enantioselective alkylation of monocyclic 5-, 6- and 7-membered lactam enolate derivatives to form α-quaternary and α-tetrasubstituted ...
Matchmaking between ketones and olefins has never been easy. Although ketones readily pair up with many reagents, thanks to their ability to deprotonate and form nucleophilic enolates, olefins ...