The drugs fenofibrate and gemfibrozil are considered fibric acid derivatives. They can reduce serum triglycerides by as much as 50% in some studies. The mechanism of action is complex. Fibrates ...

Fibrates help lower cholesterol by reducing a type of fat in the blood. Doctors use them in the management of conditions such as dyslipidemia, heart disease, and stroke. While statins can lower ...

March 25, 2011 (Pomona, California) — The use of fibrates in the US has increased steadily over the past 10 years and remained consistent in Canada, with the market share dominated by brand-name ...

The use of fibrates and fenofibrates to reduce cholesterol levels has grown sharply in the United States over the past decade, despite mounting evidence that the drugs provide little benefit, ...

Dear Doctor: My friends and I are all getting older, and I’ve noticed that some of them are on statins to lower their cholesterol. My doctor chose a fibrate for me, Lopid (gemfibrozil). What’s the ...

I recently posted a case about a 58-year old woman with multiple medical problems including obesity, hypertension, chronic kidney disease, and dyslipidemia. With a total cholesterol of 170 mg/dL ...

A major meta-analysis of fibrate drugs has shown that they reduce the risk of major cardiovascular events, mainly through prevention of coronary artery disease and the need for revascularisation ...

Sometimes diet and exercise alone can’t protect you from the risks of high triglycerides. To lower them, your body needs an extra nudge in the form of medicine. This class of medicine reduces ...

Statins lower cardiovascular risk in patients with diabetes; however, as these patients are at higher risk than other cardiovascular patients, statins merely decrease coronary event rates to the level ...

Randomized controlled trials of fibrate therapy have yielded variable results. Although these agonists of peroxisome proliferator receptor alpha (PPAR-α) are known to reduce triglyceride levels and ...

Q: My friends and I are all getting older, and I’ve noticed that some of them are on statins to lower their cholesterol. My doctor chose a fibrate for me, Lopid (gemfibrozil). What’s the difference ...

Q: My friends and I are all getting older, and I've noticed that some of them are on statins to lower their cholesterol. My doctor chose a fibrate for me, Lopid (gemfibrozil). What's the difference ...