Gleevec contains the drug imatinib, which belongs to a class of drugs called tyrosine kinase inhibitors (TKIs). Medications in the TKI drug class are targeted therapies. They affect specific proteins ...

Everyone hopes and wishes for that last-minute cancer breakthrough that will save doomed patients. It almost never actually happens. With Gleevec, it did. The once-a-day pill turned chronic ...

The fundamental importance of protein kinases is indisputable. Their central role in essential physiological processes has provoked extensive studies and has resulted in a wealth of knowledge from ...

In a study of patients with chronic myeloid leukemia, some 95 percent have survived the cancer after five years due to treatment with Gleevec, according to results published this week in the New ...

Researchers have identified specific mutations in a rogue gene that render the drug Gleevec ineffective in patients who have chronic myeloid leukemia. The studies could provide new information that ...

Imatinib has profoundly changed the natural course of chronic myeloid leukemia (CML). Much information on imatinib efficacy and safety in CML has been provided by the International Randomized Study on ...

If you have a certain type of cancer, your doctor may discuss imatinib oral tablets with you. This is a prescription drug that’s used to treat some types of blood cancer and skin cancer. Specifically, ...