Continuous twin-screw granulation offers several options for increasing production scale. Thermo Fisher Scientific explains factors to consider in scale-up projects for manufacturing oral solid-dosage ...

The characteristics of tableted solid dosage drugs often depend on the granulation process, so selecting the most appropriate granulation technique and monitoring the process are crucial Granulation ...

Pharmaceutical manufacturing practices are advancing towards a future in which continuous manufacturing processes will be the norm. Developing and applying such techniques is therefore an essential ...

Formulating drugs to ensure therapeutic consistency, enable rapid development, and allow for cost-effective scale-up has become increasingly challenging. This is especially true in the context of ...

Adopting a Quality by Design (QbD) approach for wet granulation requires manufacturers to comprehend the correlation between process variables, such as powder characteristics and equipment ...

In dry granulation, powders bind because of the application of mechanical stress. As particles are forced to be within closer proximity, entrained air is forced out, bulk density increases, and a ...