Histamine is a biogenic amine released predominantly by mast cells and basophils during immediate hypersensitivity reactions. Four receptor subtypes (H1–H4) mediate its diverse effects, with the H1 ...

When seasonal allergies strike, most people focus on pollen and the respiratory tract. They reach for antihistamines, nasal ...

Mast cells are centrally implicated in the progression of diabetic kidney disease through their roles in inflammation, fibrotic remodelling and microvascular dysfunction. In the diabetic milieu, ...

Voluntary attention to inflammation-related bodily sensations reduced the magnitude of histamine-induced skin inflammation ...

Allergic inflammation plays a big role in allergy reactions and contributes to the itching and chewing commonly seen with allergies. Histamine is an important part of this inflammatory process. The ...

We asked a doctor and dietitian to share low and high histamine foods for those with histamine intolerance. Fact checked by Emily Peterson Medically reviewed by Jessica Levinson, MS, RDN, CDN If ...

The relationship between food allergies and chronic illness represents one of the most significant yet underappreciated connections in modern health care. While conventional medicine has long ...

Curcumin, the active compound in turmeric, inhibits NF-κB, the molecular switch that tells your immune cells to release inflammatory cytokines. A 2006 review by Aggarwal and Harikumar published in ...