Obtaining prefrontal cortex biopsies during deep brain stimulation (DBS) surgery in living patients does not increase the risk of adverse events or cognitive decline compared to standard DBS ...

Understanding how the brain learns and applies rules is the key to unraveling the neural basis of flexible behavior. A new study from the University of Toyama, Japan, reveals that our ability to ...

Historically, neuroscientists and evolutionary anthropologists assumed that modern humans' disproportionately large frontal lobes and the explosive growth of our prefrontal cortex millennia ago were ...

Cognitive deficits from dorsolateral prefrontal cortex (dlPFC) dysfunction are common in neuroinflammatory disorders, including long-COVID, schizophrenia and Alzheimer’s disease, where impairments are ...

Prefrontal cortex biopsies taken for research purposes during deep brain stimulation (DBS) procedures appeared to be safe, new research has suggested. Investigators found no significant differences in ...

A traditionally overlooked type of RNA plays an important role in promoting resilience to depression-but only in females. According to a new study led by the Icahn School of Medicine at Mount Sinai, ...

An image from the research shows axons from neurons in the ACA (red) and ORB (green) innervating the visual cortex, targeting discrete layers. Vision shapes behavior and, a new study by MIT ...

The results reveal that the human frontal operculum is subdivided into 3 regions, organized on the antero-posterior axis: PCO, located at the level of the precentral gyrus and thus the premotor/motor ...

Elevated levels of a highly abundant chemical messenger in the brain are linked to a heightened sensitivity to making ...

Neuronal sequences in the medial prefrontal cortex of the brain encode critical information associated with a procedural rule. These sequences can be explored and leveraged as novel biomarkers for ...