X-chromosome inactivation varies across different areas of brains. Here, fluorescent imaging data from a mouse reveal where the father’s X chromosome is most active (white) and least active (blue). A ...

Eighty percent of patients with autoimmune diseases are female. These diseases are one of the top 10 leading causes of death for women under 65, and cases are increasing annually worldwide. There is ...

Shaped by thousands of years of evolution, the body’s immune system is a vigilant guardian primed against external infectious threats. Too much vigilance, however, and this guardian of potent cells ...

Science has revealed some of the secrets of the X chromosome, but many remain. In humans, female cells contain two X chromosomes (XX) and male cells contain one (XY). In each female cell, one X ...

The cells of female mammals randomly inactivate one X chromosome to keep gene dosage the same as in males. Does it matter which X becomes inactive? Surprisingly, it does, according to new research ...