Similarly, it is now known that live-attenuated smallpox vaccines, such as MVA and LC16m8, retain several of the genes found in VARV, many of which have been identified as potential targets of ...

The World Health Organization (WHO) has granted Emergency Use Listing (EUL) for the LC16m8 mpox vaccine, making it the second mpox vaccine to be supported by WHO following the Director-General's ...

Another vaccine, LC16m8, has been approved in Japan and limited research shows it generates antibody response to mpox without serious safety concerns. The smallpox vaccine ACAM2000 has been used ...

MVA-BN is not licensed for use in individuals under 18. The second vaccine, LC16M8, was licensed in Japan in 1975 for smallpox without age restrictions and was expanded for mpox prevention in ...

Determining Immune Correlates of Protection Against Orthopoxviruses New-generation live vaccinia viruses currently being developed as smallpox vaccines (e.g., MVA and LC16m8) were attenuated by ...