Most obese patients grow resistant to satiety signals from the hormone leptin. A new study shows that leptin sensitivity can be restored in mice, leading to weight loss. Worldwide obesity rates have ...

Obesity is often a combination of genetic and lifestyle factors. Genetics can influence metabolic pathways, appetite control, and energy storage. Leptin resistance can lead to increased appetite and ...

A study more closely links obesity to dementia, finding that leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting brain white matter in middle-aged ...

When it comes to type 2 diabetes, we tend to think we know all there is to know and are resigned to lifelong insulin injections. But its causes are not uniform throughout the world. For instance, in ...

Those little fruit flies floating around the ripening cantaloupes pack some fat between their tiny wings. They’re cold-blooded and burn their fat to warm up. “They have really beautiful fat, the flies ...

Worldwide obesity rates have more than doubled since 1990, with nearly a billion people now falling into the category. Though a complex interplay of genes, diet, and environment contribute, 90% of ...

For more than a hundred years, insulin has been the key to controlling type 1 diabetes. It has saved lives by preventing diabetic ketoacidosis (DKA), a life-threatening condition that happens when the ...