Ishikawa, Japan - The correct functioning of our cells rests upon the precise orchestration of many complex processes and organelles. Lysosomes—vital cell organelles—are enzyme-filled subunits found ...

This review focuses on the vital interconnections among lysosomes, iron metabolism, and mitochondria in osteoclasts.

Today in Nature, University of Pittsburgh researchers describe for the first time a pathway by which cells repair damaged lysosomes, structures that contribute to longevity by recycling cellular trash ...

Lysosomes are tiny sacs of digestive enzymes that declutter cells by breaking down waste. But they can also be troublesome: When their outer surface is damaged, their destructive proteins begin to ...

Lysosomes, often reductively referred to as the "garbage disposals" of cells, play a pivotal role in our cells’ digestive systems by getting rid of unwanted materials. Now in a groundbreaking study, ...

I’d love to read a creepy science fiction story where people dissolve. I asked my friend Anders Omsland if that could happen. He’s a biomedical researcher at Washington State University. He told me a ...

The duplication and division of cells is critical to keeping all multicellular organisms alive. But the opposite process is equally important: cell death. Controlled death of cells, or programmed cell ...

Accumulation of fat molecules is detrimental to the cell. Researchers from the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine), have made a breakthrough in ...

In many neurodegenerative disorders, microglia come down with a kind of indigestion, and no longer degrade lipids and other molecules. In the December 1 Science Translational Medicine, researchers led ...

C-terminal fragments of amyloid precursor protein have been blamed for endolysosomal dysfunction in Alzheimer’s disease. Now, scientists led by Wim Annaert at KU Leuven, Belgium, claim that’s because ...