Despite long-standing interest, the cellular mechanisms driving the initiation of mammary gland development have remained elusive for decades, mostly due to technical limitations in studying dynamic ...

Hormones, growth factors and several proteins ensure that development occurs in the right way, at the right time. The components that cause breast development in mammals, for example, were thought to ...

A new culture system that tests the role of chemical exposure on the developing mammary gland has found that bisphenol A (BPA) directly affects the mammary gland of mouse embryos. The study show that ...

Regulatory genes control normal and unhealthy development in mammals. Among these are miRNAs, but few have been linked explicitly to a resulting physiological process. A new study appeared online in ...

Publication in Nature Cell Biology: researchers at the Université libre de Bruxelles, ULB define for the first time the mechanisms responsible for the mammary gland development. The mammary gland is ...

In experiments with mouse tissue, UC San Francisco researchers have discovered that the adaptive immune system, generally associated with fighting bacterial and viral infections, plays an active role ...

Lab-grown organoids mimic the complexity of organs in vitro and provide insights into biology and disease. Researchers have leveraged organoids developed from mammary glands or tumors to study breast ...

Recently, we have identified a novel 1.8 kb human Notch4/Int3 RNA species (designated h-Int3sh). The h-Int3sh RNA encodes a protein that is missing the CBF1-binding region (RAM23) of the Notch 4/Int3 ...

Walter and Eliza Hall Institute researchers have discovered how the growth of milk-producing mammary glands is triggered during puberty.Sleeping stem cells in the mammary gland are awoken by a protein ...

In experiments with mouse tissue, UC San Francisco researchers have discovered that the adaptive immune system, generally associated with fighting bacterial and viral infections, plays an active role ...

Helsinki University research group used live tissue imaging for the first time to visualise the emergence of the mammary gland. Despite long-standing interest, the cellular mechanisms driving the ...