Methotrexate is a primary disease-modifying anti-rheumatic drug (DMARD) used to treat rheumatoid arthritis (RA) by reducing inflammation and suppressing the immune system. The American College of ...

Methotrexate belongs to a class of drugs called antimetabolites. This type of drug slows the growth of skin cells or cancer cells and suppresses the immune system. In addition to treating rheumatoid ...

Methotrexate is often the first medication prescribed for rheumatoid arthritis, but the NHS warns of serious side effects ...

Methotrexate is a slow-acting disease-modifying antirheumatic drug (time to maximum therapeutic response is approximately 6 months), and delayed dose escalation might result in a loss of efficacy.

People taking methotrexate should avoid alcohol because it can increase the risk of liver damage. Some NSAIDs like aspirin should not be taken with methotrexate due to possible harmful effects on the ...