The Hidetoshi Sakurai Laboratory at CiRA has successfully reproduced the pathology of Myotonic Dystrophy type 1 (DM1) using skeletal muscle cells generated from patient-derived iPS cells and ...
In a recent study published in the International Journal of Epidemiology, researchers used genetic techniques to test the causal link between glycemia, adiposity, and musculoskeletal conditions.
Facioscapulohumeral muscular dystrophy (FSHD) is a severe muscle disorder caused by aberrant DUX4 mRNA expression in skeletal muscle. DUX4 activates downstream target transcriptome, known as D4T, ...