Alpha-1 antitrypsin (AAT) deficiency is an autosomal recessive genetic disease that can lead to a number of different medical conditions. Chronic liver disease, cirrhosis, and hepatocellular carcinoma ...

Background: Early diagnosis of neonatal cholestasis is important for proper management. Making the differential diagnosis of extrahepatic from intrahepatic cholestasis as the first step for diagnosis ...

Objective: To describe the incidence and the characteristics of cholestasis in a neonatal population dependent on parenteral nutrition (PN) and to analyse additional risk factors. Methods: Monocentric ...

Biliary atresia, a progressive sclerosis of the extrahepatic biliary tree that occurs only within the first 3 months of life, is one of the most common causes of neonatal cholestasis and accounts for ...

Our laboratory conducts basic and translational research focused on the pathogenesis and treatment of neonatal liver diseases, with a primary emphasis on cholestasis and parenteral ...

To highlight the importance of actively looking for concomitant cCMV as a routine evaluation of patients presenting with cholestasis and receiving a diagnosis of an inherited liver disease, ...

February 2, 2009 (San Diego, California) — Some investigators are suggesting that obstetricians may be delivering babies too early when the mother develops cholestasis, according to a recent ...

The Translational Pediatric Nutrition laboratory led by Dr. Douglas Burrin works on basic and translational projects designed to establish how nutritional support, enteral versus parenteral, effects ...

Parenteral nutrition (PN) is a lifesaving means of nutritional support for thousands of hospitalized infants who cannot tolerate normal oral feeding due to the immaturity or surgical removal of the ...

A recent study published in Frontiers in Medicine evaluated the effects of coronavirus disease 2019 (COVID-19) quarantine on outcomes in individuals with intrahepatic cholestasis of pregnancy (ICP).