Antibiotic resistance is rising fast, killing tens of thousands each year in the U.S. alone—and scientists are racing to find ...
Researchers found three bacteriophages disable MurJ, a key cell wall transporter, by locking it outward-facing. This blocks peptidoglycan synthesis, killing bacteria and revealing a new antibiotic ...
Drug-resistant bacteria are becoming harder to treat, pushing scientists to look for new antibiotic targets. Researchers have now discovered that several unrelated viruses disable a key bacterial ...
We still do not understand exactly how antibiotics kill bacteria. However, this understanding is necessary if we want to develop new antibiotics. And that is precisely what is urgently needed, because ...
We still do not understand exactly how antibiotics kill bacteria. However, this understanding is necessary if we want to develop new antibiotics. And that is precisely what is urgently needed, because ...
Researchers at Umeå University in Sweden published a study “Breaking barriers: pCF10 type 4 secretion system relies on a self-regulating muramidase to modulate the cell wall” in mBIO that describes ...
The bacterial cell wall must be constantly remodeled in order to grow and divide. This involves the close coordination of lytic enzymes and peptidoglycan synthesis. Researchers led by Martin ...