The NFL regular season rolls into Week 10 and it starts with an NFC East battle on Thursday Night Football. Here's what to know.

Week 10 NFL picks feature Pittsburgh Steelers at Cincinnati Bengals, Kansas City Chiefs at Atlanta Falcons, and a bold over on Dolphins-Colts.

Purdy went 17-for-25 for 232 yards, two touchdowns, and one interception while adding 40 rushing yards and a touchdown in a dominant win against the Raiders. The 49ers still look like the NFC's top team with a 7-1 record, and Purdy has 1,980 passing yards and 19 total offensive touchdowns (17 passing, 2 rushing) this season.

Bet365 has Jaxon Smith-Njigba at +425 to score the first touchdown when the Seahawks visit the Raiders at Allegiant Stadium on Sunday. Odds, analysis and a best bet.

We go over the Week 10 NFL Injury Report, providing the latest updates and news, plus fantasy football analysis.

The model, which simulates every NFL game 10,000 times, is up more than $5,000 for $100 players on betting sites on top-rated NFL picks since its inception. The model entered Week 10 of the 2026 NFL season on a 62-52 run on top-rated picks dating back to 2024. Anybody following its picks at NFL betting sites could have seen strong returns.

Not only did he see only six carries for 25 yards in Week 9, but he turned seven targets into -5 receiving yards on five receptions. That is wildly inefficient. He is no longer a startable option coming off a week in which he posted just 20 yards from scrimmage.

The Cardinals miraculously edged the Rams once already. Since then, Los Angeles has won three straight and gained back Garrett, who petrified Jayden Daniels last week. Welcome to the NFL, Carson Beck.