Researchers have captured real-time "molecular movies" showing how an enzyme changes shape during catalysis. The study was ...

RFdiffusion2, RFdiffusion3, and Riff-Diff each solve different structural problems in computational enzyme design ...

Takeaki Ozawa and his team from the University of Tokyo reveal the metabolic reactions upon activating an enzyme called Akt2. In doing so, they reveal the inner workings of insulin-regulated ...

There are many chemical methods for adding medicinally helpful fluorinated alkyl groups onto molecules, but doing so with high stereoselectivity can be a challenge, especially at remote positions.

Humanity continuously emits greenhouse gases and thereby worsens global warming. Increasing research efforts go into developing strategies to convert these gases, such as carbon dioxide (CO2), into ...

Natural biological systems cannot efficiently convert waste CO₂ or its derivatives into useful building-block chemicals at a scale that can keep pace with rising atmospheric carbon. Engineer a fully ...

CABBI Postdoc Zhengyi Zhang works at the Carl R. Woese Institute for Genomic Biology (IGB) at Illinois. Using photocatalysis, Zhang and his co-authors developed a more cost-effective, eco-friendly way ...

A subtle flaw in a single brain enzyme now looks like one of the earliest sparks that can set dementia in motion. Instead of ...

In a breakthrough that defies nature, Northwestern University and Stanford University synthetic biologists have created a new ...