Bacterial ribosomes are central to protein synthesis, and their regulation is vital for adaptation to environmental stresses. Under conditions such as nutrient deprivation, cold shock or hypoxia, ...

The ribosome serves as the essential molecular machine that translates genetic information carried by messenger RNA (mRNA) into functional proteins. Comprised of two distinct subunits, the ribosome ...

Scientists report a method for stable attachment of peptides to tRNAs, which has allowed them to gain new fundamental insights into ribosome function by determining the atomic-level structures of ...

A new technique reveals ribosome cooperativity, providing new insights into protein production. Researchers from Marvin Tanenbaum’s group at the Hubrecht Institute (Utrecht, Netherlands) have ...

Inside tiny cellular machines called ribosomes, chains of genetic material called messenger RNAs (mRNAs) are matched with the corresponding transfer RNAs (tRNAs) to create sequences of amino acids ...

Proteins are absolutely essential for the survival of organisms; they carry out many functions that are critical to life. Something needs to build all of those proteins from their basic components.

Researchers from the Stowers Institute for Medical Research have discovered a new function of ribosomes in human cells that may show the protein-making particle's role in destroying healthy mRNAs, the ...

This study sheds new light on the mechanisms that maintain and regulate polyubiquitin chains on stalled ribosomes during ...

At one time or another, most of us have played with a flipbook, using our thumbs to rapidly flip a series of pictures to create an illusion of movement. Scientists use a similar technique to study the ...

“It’s a really clever paper and there’s a huge body of work that underlies it,” said molecular biologist Harry Noller of the University of California, Santa Cruz, who was not involved in the work. “It ...

In the 1940s, scientists at the recently established National Cancer Institute were trying to breed mice that could inform our understanding of cancer, either because they predictably developed ...

Inside tiny cellular machines called ribosomes, chains of genetic material called messenger RNAs (mRNAs) are matched with the corresponding transfer RNAs (tRNAs) to create sequences of amino acids ...