Rates of septic shock, a serious complication of sepsis, are on the rise. With only antibiotics and symptomatic treatment available, biotech Inotrem hopes its investigational asset could be the first ...

Septic shock is the most severe complication of sepsis, which is a reaction to an infection. A person with sepsis may go into septic shock, which can cause organ failure and other life threatening ...

Patients with heart failure frequently suffer from fluid overload, and for those with heart failure with reduced ejection fraction (HFrEF) also suffering from septic shock—a condition often treated ...

In 2010, SOAP II (Sepsis Occurrence in Acutely Ill Patients II) produced a blinded, randomized, multicenter trial that hypothesized that norepinephrine may be a better first-line vasopressor agent ...

A multi-institutional research team has demonstrated how AI and machine learning can optimize therapy selection and dosing for septic shock, a life-threatening complication that is the leading cause ...

There have been conflicting reports on the efficacy of recombinant human activated protein C, or drotrecogin alfa (activated) (DrotAA), for the treatment of patients with septic shock. In this ...

Cirrhosis, malignancy, and acute kidney injury are among the clinical factors associated with early mortality in patients with septic shock.

After a single-center trial and observational studies suggesting that early, goal-directed therapy (EGDT) reduced mortality from septic shock, three multicenter trials (ProCESS, ARISE, and ProMISe) ...

2. Overall, dysrhythmias were more common with dopamine. Patients with cardiogenic shock demonstrated a significantly higher mortality rate with dopamine than with norepinephrine. Dopamine-induced ...