New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...

Early in the development of sperm, a strange event happens: the X and Y chromosomes condense into tight packages and are sequestered away from the other 44 human chromosomes. If any part of this ...

Gene expression related to fertilization, sperm motility, and sperm structure in the testes of Tle6 -deficient mice showed an overall increase. Together, the findings of this study highlighted the ...

Two new landmark studies show how a seeming tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published March 3 as two papers in ...

Sperm DNA fragmentation is a recognized factor in male infertility with direct implications for embryo development, implantation and pregnancy outcomes. Historically, standard semen analysis has not ...

There are many potential causes of infertility, and it can be challenging to pin down just what the problem is when a couple is having trouble getting pregnant. Now, researchers show that a few key ...

A Utah biotech startup says it has grown functional human sperm in a lab and used it to create early embryos—a development that, if validated, could dramatically expand options for men with severe ...

Clinical data reveals male factors contribute to half of all infertility cases, shifting the focus toward earlier ...

The propulsion for mammalian sperm swimming is generated by flagella beating. Microtubule doublets (DMTs) along with microtubule inner proteins (MIPs) are essential structural blocks of flagella.

Recent research shows that a father’s health, lifestyle, and environment can influence his children’s development, even ...

Researchers showed how what appears to be a tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published as two papers in Nature ...