The research team included, back row, from left, Shih-I (Harry) Tan, Nilmani Singh, Aashutosh Boob, and front row, from left, Teresa Martin, Li-Qing Chen, and Huimin Zhao. The mitochondrion, often ...

Bile acids are essential signaling molecules derived from cholesterol metabolism in the liver and are crucial for the digestion and absorption of fats. These molecules undergo further modification in ...

Scientists have discovered that boosting the COX7RP protein enhances cellular energy efficiency and significantly extends ...

A research collaboration has found that besides regulating the fusion of mitochondria, Mitofusin 2 also ensures protein quality control. This discovery could open up new routes to treating ...

Scientists uncovered how the amino acid leucine enhances mitochondrial efficiency by preserving crucial proteins that drive energy production. By downregulating the protein SEL1L, leucine prevents ...

In 1817, a British physician named James Parkinson published An Essay on the Shaking Palsy, describing for the first time cases of a neurodegenerative disorder now known as Parkinson’s disease. Today, ...

Tiny biological batteries known as mitochondria keep the body's cells running smoothly, and their gradual decline is linked to a wide range of age-related diseases. Now scientists think they have ...

Maintaining mitochondrial DNA (mtDNA) integrity is crucial for cardiomyocyte function, and its disruption plays a significant role in ischemia/reperfusion (I/R) injury. This review sheds light on the ...

As life expectancy continues to climb globally, the focus of many people has moved from longevity alone to living in good health. This has drawn attention to the need to extend "healthspan," the ...