Making chiral tertiary alcohols has always been a tricky endeavor. Now, a research group led by Varinder Aggarwal, a chemist at the University of Bristol, in England, reports a new strategy using ...

A research group at Nagoya University in Japan has developed a new catalyst that promises to revolutionize the asymmetric synthesis of pharmaceuticals called chiral macrocyclic dilithium(I) salt. It ...

It’s turnabout time for triply substituted alcohols in a new reaction, which flips the configuration of an alcohol’s central carbon as the compound is transformed into an isonitrile. The reaction ...

Alcohols are organic compounds characterized by the presence of one or more hydroxyl (-OH) groups attached to a carbon atom. They play vital roles as building blocks in various chemical processes, ...

The authors describe several examples of using asymmetric hydrogenation and biocatalysis for synthesizing several secondary alcohol compounds. Chiral secondary alcohols are important intermediates and ...