As humans age beyond early adulthood, their physical and mental functions tend to slowly worsen over time. One of the most common sources of severe mental decline in older adults are neurodegenerative ...

A new study delving into the genetic drivers of a rare and aggressive childhood cancer called Malignant Peripheral Nerve Sheath Tumor (MPNST) has revealed metabolic frailties in the cancer cells that ...

Stimulating a key metabolic pathway in T cells can make them work more effectively against tumors when combined with immune checkpoint inhibitor therapy, according to a preclinical study. The findings ...

Researchers have discovered that activating the pentose phosphate pathway makes antitumor CD8+ T cells more likely to stay in an immature, stem-like, “precursor” state. Combining this metabolic ...

Parkinson’s disease may begin reshaping the body’s chemistry years before the first tremor or stiffness appears. A growing body of peer-reviewed research now ties specific metabolic disturbances, from ...