A newly discovered pair of stem cell lineages drives the formation of both tooth roots and the bone that anchors them. Understanding how these cells switch roles could pave the way for regenerating ...

Two distinct stem cell lineages that drive tooth root and alveolar bone formation have been identified by researchers from Science Tokyo. Using genetically modified mice and lineage-tracing techniques ...

Tooth root development relies on precise coordination of cellular signals, yet the underlying mechanisms remain unclear. Researchers have uncovered how two proteins, Gli2 and Gli3, work together to ...

Susanna Sova studying a pig molar cusp that was modelled in the study. Credit: Jukka Jernvall The tooth is the most mineralized tissue in the mammalian body and holds information about the creature it ...

A system of opposing genetic forces determines why mammals develop a single row of teeth, while sharks sport several, according to a study published today in the journal Science. When completely ...

Researchers at the University of Zurich Center for Dental Medicine recently studied the Notch pathway’s role in the evolution of tooth morphology, with their results being published in Cellular and ...

Two distinct stem cell lineages that drive tooth root and alveolar bone formation have been identified by researchers from Science Tokyo. Using genetically modified mice and lineage-tracing techniques ...

Tooth development relies on sequential and reciprocal interactions between the epithelial and mesenchymal tissues, and it is continuously regulated by a variety of conserved and specific ...

Scientists have gotten one step closer to growing replacement teeth in the lab — a development that could pave the way for new alternatives to unpleasant dental fillings and root canals. The team ...