The alternative text for this image may have been generated using AI. Figure 2: Single-allele duplication of α-tryptase–encoding sequence in TPSAB1 is associated with elevated basal serum tryptase ...

Medically reviewed by Marla Anderson, MD Indolent systemic mastocytosis (ISM) symptoms appear when mast cells release ...

In a decade-long study, a ratio of serum acute tryptase to serum baseline tryptase above 1.74 showed superior diagnostic performance compared with the current consensus formula, which requires serum ...

Please provide your email address to receive an email when new articles are posted on . Based on these risk factors, providers should prolong their monitoring of these patients, Terence Langlois, ...

Please provide your email address to receive an email when new articles are posted on . Patients with alpha tryptase had more anaphylaxis than patients who only had B-tryptase. 65% of patients with ...

"Here, we showed that generating a clinical registry and standardizing and centralizing evaluations for SM at [centers for excellence] increased the frequency of timely and correct clinical and ...

Reference ranges for basal serum tryptase (BST) are an excellent guide to determining whether a patient’s BST value is normal, per their specific tryptase genotype. If the BST is elevated based on the ...

--Data strongly support expanding development into mast cell driven diseases----Data presented in a late-breaking session at EAACI Annual Congress 2020-- CDX-0159 demonstrated a favorable safety ...

The use of PARP inhibitors as single agents and as chemosensitizers in sporadic pancreatic cancer. Farletuzumab, a monoclonal antibody against folate receptor alpha (FRα), does not block folate or ...

Scientists at the National Institutes of Health have identified a genetic explanation for a syndrome characterized by multiple frustrating and difficult-to-treat symptoms, including dizziness and ...