BUFFALO, N.Y. — One class of drugs that has shown promise in treating diseases ranging from lung cancer to COVID-19 are targeted covalent inhibitors (TCIs). These small molecule drugs form covalent ...

Covalent inhibitors are a specialized class of small molecules designed to form chemical bonds with their target proteins, often resulting in prolonged target engagement and enhanced potency. The ...

Antimony-nitrogen interactions yield materials with enhanced stability and the ability to self-heal in aqueous environments ...

In a recent paper in ACS Central Science, researchers report a strategy for targeting covalent modifications to specific sites on proteins. The modifier molecules use an antibody to target a protein ...

Researchers from North Carolina State University and the University of Houston have achieved sustained self-healing of a composite material. The findings promise to extend the lifetime of aircraft and ...