A parasite which has devastating impacts on agriculture and human health is the first pathogen to have its proteins located and mapped within its cells -- providing clues to their function and helping ...

Evolution of bacterial pathogen populations has been detected in a variety of ways including phenotypic tests, such as metabolic activity, reaction to antisera and drug resistance and genotypic tests ...

Co-evolution between host and pathogen is, in principle, a powerful determinant of the biology and genetics of infection and disease. Yet co-evolution has proven difficult to demonstrate rigorously in ...

A new way to map the spread and evolution of pathogens, and their responses to vaccines and antibiotics, will provide key insights to help predict and prevent future outbreaks. The approach combines a ...

Tuberculosis is the world's deadliest infectious disease, due in part to its ability to hide out for years in the lungs before starting an infection. Now, a new computational method developed by ...

Combining genomic data and human travel patterns over a 14-year period in South Africa reveals key insights into the spread, evolution and resistance patterns of a major bacterium behind pneumonia and ...

Critical- and high-priority pathogens in the food chain represent a persistent and evolving threat to global public health. These microorganisms are ...

In addition to identifying 4,012 genes, comprising 84 percent of the sequence, the work reveals an unusually dynamic genome, with genes added, moved, and silenced into pseudogenehood. "This ...

A committee-supported project or activity that has been completed and for which output dissemination has begun. Its committee has been disbanded and closeout procedures are underway. A planning ...

A new study in South Africa shows that before antiretroviral therapy (ART) became widely available, HIV was driving rapid genetic changes in human immunity genes. By sharply reducing deaths and mother ...

As antibiotic resistance accelerates, ESKAPE pathogens reveal how hospital superbugs survive treatment, spread across ...