Ribosomes are fundamental molecular machines that translate mRNA sequences into polypeptides, ensuring the proper synthesis of proteins essential to cellular function. However, the fidelity of protein ...

The discovery of ribosomes dates back to the 1950s, when George Palade first observed dense particles in the cytoplasm of cells using electron microscopy. These particles were later named "ribosomes" ...

• From the cellular perspective, organ growth is determined by production and growth of cells. Uncovering how these two processes are coordinated is essential for understanding organogenesis and ...

Proteins are absolutely essential for the survival of organisms; they carry out many functions that are critical to life. Something needs to build all of those proteins from their basic components.

Aging leads to a decline in cellular fitness and loss of optimal protein function. The mechanisms underlying how aging causes proteins to aggregate have not been fully understood. Using models of ...

These spots are socRNAs being translated by ribosomes in a cell. They get brighter over time, showing active translation. The complex, which includes the socRNA and ribosome, is attached to the plasma ...

A team of researchers used a new technique, called high-resolution template matching, or HRTM, to uncover in unprecedented detail the movement of ribosomes -- the molecular structures that synthesize ...

When cells are stressed by heat, toxins, inflammation, or other challenges, most cellular processes, including protein production, are temporarily shut down to help the cell survi ...

Berkeley -- A new, sharper picture of the nano-machine that translates our genetic program into proteins promises to help researchers explain how some types of antibiotics work and could lead to the ...

New research shows at atomic detail how antibiotics affect the process of protein production inside bacteria. The study uses cryo-electron tomography to observe the dynamics of the translation ...