Studying the process of brain formation illuminates just how much of development is a series of tiny miracles. Only a few ...

When a vertebrate embryo develops, a group of cells self-organizes into the neural tube, eventually becoming the brain and the spinal cord. This involves specific signals, but how these signals ...

Anencephaly is a type of neural tube defect. During pregnancy, your baby's brain and spine start to form as a flat disk of cells. This flat disk rolls into a tube-like structure called the neural ...

The neural tube gives rise to a rapidly developing 3D structure of the early brain that grows almost 10x fold in size from 3-5mm (E27) to 27-31mm by week 8.

The p53 gene stops tumors from forming. Now researchers have found that the tumor-suppressing gene also has a critical role in the formation of the neural tube in female embryos. The neural tube is ...

The body transforms dietary folic acid into folate, which mediates normal neural tube development. The researchers discovered that the drug interferes with the binding of folate to its receptor, thus ...

Neural tube defects consist of abnormalities in the development of the brain and spinal column. The NICHD-funded study, which began in 2014 in Botswana, was used to track birth outcomes, including ...

New research has revealed how the famous tumour suppressor gene p53 is surprisingly critical for development of the neural tube in female embryos.

Spina bifida is a serious congenital condition caused by abnormal neural tube development during early pregnancy. While folic acid supplementation has dramatically reduced its incidence, cases ...

HIV drug doluteglavir interferes with the binding of folate to its receptor, thus promoting neural tube defects. Folic acid supplementation can mitigate the risk of the medication in an animal model.