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Chemidroplet is a chemical tool, that fused the BTB-containing domain to the multivalent DNA binding domain (DBD) and intrinsically disordered regions (IDRs) to readily control the LLPS of these ...
Liquid-liquid phase separation is not a precursor to formation of amyloid fibrils, a pathological hallmark of Parkinson's disease, shows study. Rather, the formation of protein into liquid droplets ...
The common commensal gut bacterium Bacteroides thetaiotaomicron uses phase separation of the transcription termination factor Rho to colonize and thrive in the mammalian gut, according to a new study ...
Prion-like RNA binding proteins (RBPs) such as TDP43 and FUS are largely soluble in the nucleus but form solid pathological aggregates when mislocalized to the cytoplasm. What keeps these proteins ...
Chun-Wei Lin, Laura M. Nocka, Brittany L. Stinger, Joseph B. DeGrandchamp, L. J. Nugent Lew, Steven Alvarez, Henry T. Phan, Yasushi Kondo, John Kuriyan, Jay T. Groves ...
Slurry-based absorption–adsorption enables efficient ethane recovery from natural gas, reducing energy use while ensuring ...