Medscape

Third- and Further-line Therapy in Advanced Non-small-cell Lung Cancer Patients

The most widely studied targeted therapies for the third- and further-line treatment of NSCLC are EGFR inhibitors: gefitinib, erlotinib, cetuximab and afatinib (Table 3). The most important predictive ...
The American Journal of Managed Care

Navigating First-Line Therapy Guidelines and Treatment Considerations in High-Risk Cytogenetics

Panelists discuss how NCCN guidelines are expected to incorporate quadruplet-based regimens as reasonable treatment approaches for transplant-ineligible patients, while emphasizing the need for ...
Healio

Second-line therapy may not be offered enough to patients with advanced fibrosis

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Monthly Prescribing Reference

Fecal Microbiota Transplantation Could Be First-Line Therapy for C. Difficile

Clinical cure and no disease recurrence within 60 days without additional treatment was observed in 66.7% of 51 patients receiving FMT vs 61.2% of 49 patients receiving vancomycin. HealthDay News — ...
ascopubs.org

Second-Line Endocrine Therapy With or Without Palbociclib Rechallenge in Patients With Hormone Receptor–Positive/Human Epidermal Growth Factor Receptor 2–Negative Advanced ...

Characteristics of Patients and Prognostic Factors Across Treatment Lines in Metastatic Colorectal Cancer: An Analysis From the Aide et Recherche en Cancérologie Digestive Database Between April 2019 ...
Medscape

Vedolizumab Beats Infliximab as Second-Line Therapy for Ulcerative Colitis

BERLIN — Ulcerative colitis (UC) patients who fail on first-line therapy appear to have better outcomes with vedolizumab (Entyvio) than with infliximab, suggests EFFICACI, the first trial directly ...
Cure Today

Mesothelioma Treatment Options by Stage and Line of Therapy

Asbestos-associated latency necessitates careful exposure history, and symptom patterns differ between pleural and peritoneal disease, often reflecting effusion or serosal thickening. Tissue ...
ascopubs.org

Transarterial chemoembolization combined with atezolizumab plus bevacizumab versus transarterial chemoembolization combined with lenvatinib plus sintilimab as first-line ...

Surufatinib combined with gemcitabine and cisplatin and immune checkpoint inhibitor (ICI) for unresectable locally advanced or metastatic intrahepatic cholangiocarcinoma. Updated results of anlotinib ...
Business Wire

TUKYSA Added to First-Line Maintenance Therapy Extends Median Progression-Free Survival by Over 8 Months in Patients with HER2+ Metastatic Breast Cancer

NEW YORK--(BUSINESS WIRE)--Pfizer Inc. (NYSE: PFE) today announced detailed results from the Phase 3 HER2CLIMB-05 trial of the tyrosine kinase inhibitor TUKYSA ® (tucatinib) as part of an ...