Whilst the ultimate outcome of the lytic cycle is production of new phage progeny and death of the host bacterial cell, this is a multistep process involving precise coordination of gene transcription ...

Phage infection occurs via two alternate cycles, initiated by the injection of phage DNA or RNA into the host. In the lytic cycle, this is translated to produce phage proteins that hijack the host ...

We observed heterogeneous 5mC epiallele patterns around EBV genomic CTCF binding sites and lytic gene transcriptional start sites. “These results highlight the importance of 5mC in maintaining ...

The lytic and lysogenic cycles are the two main phases of a virus’ infective lifecycle and route to replication. The lytic cycle, or virulent infection, involves a virus taking control of a host cell ...

“Our findings demonstrate the importance of the HER/ERBB family of kinases and other kinases to regulate KSHV life cycle transition,” said Dr. Olson. The working model for HER/ERBB signaling during ...

The HCMV lytic replication cycle has an ∼96-h duration in vitro in fibroblasts that culminates in infectious virions and destruction of the infected cell (7). Variability exists in length of ...

Moreover, to confirm cell cycle dysregulation is important for KSHV replication, lytic cells were treated with various known cell cycle inhibitors. Arrest in the G2/M phase through RO‐3306 and ...

Results show that even for cars registered today, battery electric vehicles (BEVs) have by far the lowest life-cycle GHG emissions. As illustrated in the figure below, emissions over the lifetime of ...

Recently, a small-molecule communication mechanism was discovered in a range of Bacillus -infecting bacteriophages, which these temperate phages use to inform their lysis-lysogeny decision. We present ...