Mendelian randomization (MR) studies using diseases as exposures are increasingly prevalent although any observed associations do not necessarily imply effect of diseases. To illustrate this challenge ...
Mendelian randomization is a method for causal inference that leverages the random inheritance of alleles as instrumental variables to estimate the causal effects of exposures on outcomes 1,2,3,4 (Box ...
Introduction to Mendelian randomization, the problems with using traditional observational studies to investigate causality, and Randomized controlled trials as the gold standard for causal research.
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