Iranian missiles have again evaded Israel’s sophisticated aerial defense array, striking southern Israel’s main hospital as well as residential areas in the country’s populous center.

It was the second attack on Isfahan as the conflict enters a second week, killing at least 430 in Iran and 24 in Israel.

At least seven people were killed and more than 100 injured when an Iranian ballistic missile hit Bat Yam, just south of Tel Aviv, overnight on Sunday, domestic media reported. Other reports put the death toll at six people. Israel's police said residential buildings took a "direct hit that caused extensive damage."