Inhibition of BRSK2 attenuated lung fibrosis in cellular and animal models, identifying it as a potential therapeutic target for IPF.

Chronic lymphocytic leukemia (CLL) is a mature B-cell hematological malignancy characterized by progressive clonal proliferation of B lymphocytes in the peripheral blood, bone marrow, and lymph nodes.

The study will investigate real-life prescribing practices and outcomes to identify knowledge gaps and improve drug access for patients. A new study is recruiting patients with the aim of evaluating ...

Patients with combined diagnoses of ATTR-CM and aortic stenosis were at an increased risk of hospitalization and death, a study found.

A risk model comprised of 18 mitochondria-related genes (MRGs) offers the potential to provide personalized prognostic assessment and to guide treatment for patients with diffuse large B-cell lymphoma ...

Almost half of patients were paying for additional private health insurance for their disease. The role of social determinants of health in autoimmune liver diseases such as primary biliary ...

New research indicates that obinutuzumab is a potentially effective and cost-effective treatment for patients with rituximab-resistant AAV. Obinutuzumab therapy demonstrated immunological superiority ...

The relationship between RA and AAV—two autoimmune disorders—needs further exploration. Rheumatoid arthritis (RA) is found to often precede the diagnosis of antineutrophil cytoplasmic antibody ...

Fewer than one-fifth of the study population had an alloimmunization diagnosis code in their medical record. Almost 7% of hemolytic disease of the fetus and newborn (HDFN) cases due to Rhesus ...

Even women who had a pregnancy impacted by HDFN indicated they would accept a life-saving transfusion at the risk of future pregnancy complications. Life-saving transfusions of Rhesus D (RhD)-positive ...