In addition to increasing vaccine coverage in older adults, they need to monitor the changing epidemiology of pneumococcal serotypes causing invasive disease. [134] In the face of these changes ...

Discover the importance of adult vaccination in India, the barriers faced, and the urgent need for prioritization.

Antibiotic-resistant bacteria is a serious public health threat. Understanding the biology of these bacteria--such as how they synthesise their protective capsules--is essential for developing new ...

Antibiotic-resistant bacteria are a serious public health threat. Understanding the biology of these bacteria—such as how ...

This made it possible to produce a very complex, but practical, 23-valent polysaccharide vaccine against the disease 9,10. This approach reached its limits when conjugate vaccines were developed.

The program will offer one dose of the 13-valent pneumococcal conjugate vaccine (PCV13) and one dose of the 23-valent pneumococcal polysaccharide vaccine (PPV23). PCV13, a safe 13-serotype inactivated ...

The development by Wyeth of the vaccine Prevnar, as well as being a commercial success, was also a technological triumph. Conceptually, the approach was not new; pneumococcal polysaccharide ...

The O-specific polysaccharide of Klebsiella pneumoniae in patients with bloodstream infections is immunogenic, and its closely related subtypes are cross-reactive.

SINGAPORE: Antibiotic-resistant bacteria pose a significant threat to public health, and researchers from the Yong Loo Lin School of Medicine at the National Un ...

Antibiotic-resistant bacteria is a serious public health threat. Understanding the biology of these bacteria -- such as how they synthesise their ...

Conventional conjugate vaccines use covalent bonding to join the polysaccharide and protein antigens, which affects the way both are presented to the immune system. The phase 2 trial involved more ...