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rmdopen.bmj1d
Non-pharmacological interventions to promote work participation in people with rheumatic and musculoskeletal diseases: a systematic review and meta-analysis from the EULAR ...
Objective To summarise the evidence on effectiveness of non-pharmacological (ie, non-drug, non-surgical) interventions on work participation (sick leave, work status and presenteeism) in people with ...
rmdopen.bmj1d
Combining patient-reported outcome measures to screen for active disease in rheumatoid arthritis and psoriatic arthritis | RMD Open
Introduction. Current management guidelines for rheumatoid arthritis (RA) and psoriatic arthritis (PsA) recommend a treat-to-target (T2T) approach.1 2 In a T2T approach, treatment is adjusted if the ...
rmdopen.bmj1d
Upadacitinib in active ankylosing spondylitis: results of the 2-year, double-blind, placebo-controlled SELECT-AXIS 1 study and open-label extension | RMD Open
Introduction Long-term safety and efficacy of upadacitinib in patients with active ankylosing spondylitis (AS) has not been previously reported.Methods In SELECT-AXIS 1, patients receiving placebo ...
rmdopen.bmj1d
Association between osteoarthritis and dyslipidaemia: a systematic literature review and meta-analysis - RMD Open
Objectives We aimed to investigate the prevalence of dyslipidemia in patients with osteoarthritis (OA) and whether OA and dyslipidemia are associated.Methods We performed a systematic literature ...
RMD Open1d
Association between glucose intolerance and psoriatic arthritis features
Patients with psoriatic arthritis (PsA) have a higher prevalence of diabetes mellitus (DM) compared to the general population ...
rmdopen.bmj1d
Imaging in diagnosis, outcome prediction and monitoring of large vessel vasculitis: a systematic literature review and meta-analysis informing the EULAR recommendations - RMD Open
Objectives To perform a systematic literature review on imaging techniques for diagnosis, outcome prediction and disease monitoring in large vessel vasculitis (LVV) informing the European League ...
rmdopen.bmj1d
Therapeutic implications of the anergic/postactivated status of B cells in systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is characterised by numerous abnormalities in B lineage cells, including increased CD27++ plasmablasts/plasma cells, atypical CD27-IgD- B cells with increased CD95, ...
rmdopen.bmj2d
Single-cell RNA-sequencing analysis reveals the molecular mechanism of subchondral bone cell heterogeneity in the development of osteoarthritis - RMD Open
The cellular composition and underlying spatiotemporal transformation processes of subchondral bone in osteoarthritis (OA) remain unknown. Herein, various cell subsets from tibial plateau of patients ...
rmdopen.bmj3d
Four trajectories of 24-hour urine protein levels in real-world lupus nephritis cohorts - RMD Open
Abstract Objectives A 24-hour urine protein (24hUP) is a key measurement in the management of lupus nephritis (LN); however, trajectories of 24hUP in LN is poorly defined.Methods Two LN cohorts that ...
rmdopen.bmj3d
Performance of the proposed ACR–EULAR classification criteria for systemic lupus erythematosus (SLE) in a cohort of patients with SLE with neuropsychiatric symptoms - RMD Open
Systemic lupus erythematosus (SLE) is a heterogenic connective tissue disease with a broad spectrum of clinical and laboratory manifestations. Due to this heterogeneity, SLE remains challenging to ...
rmdopen.bmj4d
Patient-reported outcomes as end points in clinical trials in rheumatoid arthritis - RMD Open
There is a growing interest in patient-reported outcomes (PROs) in rheumatology, which goes with a global trend for more ‘patient-centred care’. This review considers the use of PROs in trials, ...
rmdopen.bmj4d
ADA2 deficiency: case report of a new phenotype and novel mutation in two sisters - RMD Open
The objective of this paper is to describe the phenotype compound heterozygote for mutations in CECR1 in two children. We describe the clinical and immunological phenotype, including the assessment of ...