Arginase belongs to the ureohydrolase family of enzymes. Arginase catalyzes the fifth and final cytosolic step in the urea cycle, a series of biochemical reactions in mammals during which the …

The arginase enzyme developed in early life forms and was maintained during evolution. As the last step in the urea cycle, arginase cleaves l-arginine to form urea and l-ornithine.

Arginase, a ubiquitous enzyme Arginase is a manganese metalloenzyme that catalyzes the conversion of L-arginine to L-ornithine and urea. It is found in bacteria, yeasts, plants, …

Oct 17, 2024 · This Review provides an overview of arginine and arginase function in immune cells, at the steady state and during disease.

Jul 28, 2025 · Arginase 1’s most recognized function is its involvement in the urea cycle, a metabolic pathway in the liver. This cycle detoxifies ammonia, a highly toxic byproduct from …

Aug 3, 2023 · Binuclear manganese metalloenzyme that catalyzes hydrolysis of arginine to ornithine and urea (Wikipedia: Arginase [Accessed 3 August 2023) Also called liver arginase

Here we review involvement of arginase in cardiovascular and nervous system dysfunction and discuss potential therapeutic interventions targeting excess arginase.

Arginase is an enzyme that catalyzes the hydrolysis of arginine, an amino acid, into urea and ornithine in the urea cycle. This reaction is crucial for the removal of excess nitrogen from the …

Oct 8, 2022 · In this review, we summarize the features and functions of arginase, the roles of arginase in cells of vascular and cardiac system, as well as in the development of CVDs.

Jul 25, 2020 · Abstract Arginase is a widely known enzyme of the urea cycle that catalyzes the hydrolysis of L-arginine to L-ornithine and urea. The action of arginase goes beyond the …